49ers Next Game 2025. 26 rows espn has the full 2025 san francisco 49ers regular season nfl schedule. The schedule includes opponents, date, time, and tv network.

Here’s a look at every team the san francisco 49ers will play on the 2025 nfl schedule, for every game from week 1 through week 18. We’re getting ahead of ourselves here, but the nfc championship game will be on sunday, january 28, at 3:30 p.m.